IMAGING OF NEAR-INFRARED FLUORESCENCE, ABSORPTION, AND SCATTER IN TURBID MEDIA A Thesis
نویسندگان
چکیده
Milstein, Adam B. Ph.D., Purdue University, August, 2004. Imaging of near-infraredfluorescence, absorption, and scatter in turbid media. Major Professor: Charles A.Bouman and Kevin J. Webb.A nonlinear, Bayesian optimization scheme is presented for reconstructing fluo-rescent yield and lifetime, the absorption coefficient, and the diffusion coefficient inturbid media, such as biological tissue. The method utilizes measurements at boththe excitation and emission wavelengths for reconstructing all unknown parameters.The effectiveness of the reconstruction algorithm is demonstrated by simulation andby application to experimental data from a tissue phantom containing the fluorescentagent indocyanine green.
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